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Design and validation of a histological scoring system for nonalcoholic fatty liver disease

RESEARCH SQUARE

As described in Results and Discussion, at pH 7.9, a 20uM niclosamide nasal solution is within the natural pH range for the nasopharynx and, at pH 9.1, a higher concentration 300M throat spray is at a tolerable pH for the oropharynx

The growing influence of GLP-1 therapies may be a catalyst for some of those shifts

45 Currently, the strategy of multiple receptor stimulation is actively expanding indications in metabolic disorders, particularly in MASLD, and some medications have reported more potent therapeutic efficacy compared to single GLP-1RA

Although the activation of autophagy has been previously proposed as a viable therapeutic approach for patients infected with Mtb, recent findings cast uncertainty on this hypothesis and impede the progression of further research