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doi: 10.1038/nrd781

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The advisory committee focused on lab studies showing that MOTS-c has the potential to help treat obesity and osteoporosis, but there is very little evidence from human trials to support its safe, effective use

To put it plainly: if low B12 was one of the things holding you back, addressing it can help you show up better for the diet and exercise work that actually drives results

One commenter emphasized the importance of engaging frontline clinicians and staff in future refinements and cautioned that changes to the Overall Hospital Quality Star Rating, such as a star reduction, could discourage transparency and self-reporting of safety events

The credibility signal is academic: its products are cited across many peer-reviewed papers