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Some clinical discussions suggest that GHRH analogs like Sermorelin may produce GH release patterns more similar to natural pulsatile secretion since they work through the endogenous pathway

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This dual mechanism explains why nausea timing is so predictable

ACS Chem Neurosci 12:573580 Zordoky BN, Sung MM, Ezekowitz J, Mandal R, Han B, Bjorndahl TC, Bouatra S, Anderson T, Oudit GY, Wishart DS, Dyck JR, Alberta H (2015) Metabolomic fingerprint of heart failure with preserved ejection fraction

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