Z., Shati, A
10.1038/sj.bjp.0705781 56 WangL.LiA.LiuY.ZhanS.ZhongL.DuY.et al (2020)
Calcineurin (tacrolimus and pimecrolimus) inhibitors may be prescribed to the areas of skin that are more sensitive, such as the face and neck, to decrease immune activity over the skin
Lower doses (600mg) show benefit but with reduced magnitude
Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo
[15] [24] [25] Evidence supporting its use in low back pain, cancer pain, and neuropathic pain is insufficient