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108 Moreover, the -HB could inhibit nuclear factor B (NF-B) signaling, 109 an upregulated inflammatory pathway associated with the pathogenesis of T2DM

These results are important from a clinical perspective as a reduction in food intake accompanied by weight loss is a desirable outcome in an obese patient

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It comprises more than 90% of the total cations at its normal plasma concentration of approximately 142 mEq/liter

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