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doi: 10.1007/s00405-019-05635-x

However, TMAO inhibited the activity of pyruvate dehydrogenase (PDH) and weakened the oxidation of pyruvate in mitochondria, which impaired production of ATP (101)

Statistical analysis In this study, both cell and animal experiments were conducted using a blinded design

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However, the following are possible: Mild nausea or stomach discomfort when taken on an empty stomach