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Sachdev, K

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that typifies an entire cluster of autoimmune diseases , known as lupus-associated

Because of their peptide structure, GLP-1 receptor agonists are susceptible to poor gastrointestinal permeability, cytosolic metabolism, and hepatic clearance mechanisms that result in poor oral bioavailability

To obtain a GLP-1RG s complex with good homogeneity and stability, we used the NanoBiT tethering strategy, in which the C terminus of GLP-1R was directly attached to LgBiT subunit followed by a TEV protease cleavage site and a double MBP tag

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