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12 Other multireceptor agonists are in development

GLP-1 stands for glucagon-like peptide-1, a hormone your body naturally produces after eating

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Sorafenib and erastin can activate the NFE2L2 pathway, resulting in the expression of antioxidant genes such as quinone oxidoreductase 1 (NQO1) and metallothionein 1G (MT1G) in HCC cells (87, 89)

Guedes FRCM, Maia CF, da Silva BRS et al (2021) Exogenous 24-Epibrassinolide stimulates root protection, and leaf antioxidant enzymes in lead stressed rice plants: central roles to minimize Pb content and oxidative stress

Long-term data shows sustained benefits when patients continue treatment, with weight regain typically occurring only after medication discontinuation