Primary care companion to the Journal of clinical psychiatry, 4(1), 30
GLP-1 receptor agonists are licensed in the UK for type 2 diabetes and weight management, including semaglutide, dulaglutide, and liraglutide These medications reduce HbA1c by approximately 1.01.5 percentage points and improve both fasting and post-meal glucose levels Weight loss associated with GLP-1 therapy can lead to secondary improvements in insulin resistance, particularly through reduction of visceral fat Common side effects include gastrointestinal symptoms such as nausea, vomiting, and diarrhoea, which typically diminish over several weeks NICE recommends continuation only if patients achieve at least 1.0 percentage point HbA1c reduction within six months of treatment initiation Patients with diabetic retinopathy require close monitoring, and GLP-1 medications should be discontinued at least two months before planned pregnancy Table of Contents What Are GLP-1 Receptor Agonists and How Do They Work
While sports supplements can enhance performance, they should only be used as a supplement, not a substitute for a proper diet and quality recovery
this exploits the fact that a combination of drugs causes effects on different targets
Gaede P, Vedel P, Parving HH, Pedersen O
It may be necessary to schedule meals or use liquid nutrition to get enough calories, even when not hungry
