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A 5-year longitudinal study showed that FTO gene polymorphisms can lead to premature rebound of ghrelin (an appetite-promoting hormone) and a hypersensitive brain response to food stimuli, thereby weakening the appetite-suppressing effect of weight loss interventions [79]

Conclusion Over the past years, GLP-1 antagonists have become a game-changer in weight management, offering a powerful tool for those struggling with obesity or Type 2 diabetes

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Combined with diet changes and increased exercise, this can help you lose weight

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Then, if one adds the additional use cases, which will admittedly come only in a few years, and additional geographies, we see potential for medium-term expectations to continue moving upwards