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The approval of this new class of weight loss medications advances the case towards treating obesity as a disease, but these medications are meant to be used alongside lifestyle changes such as nutrition and exercise

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The World Health Organization (WHO) has classified A

Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

The 1416 region (residues 329456) was poorly resolved at higher contour levels and was modelled based on density observed at lower contour levels (Supplementary Fig

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