Disrupted ROS additionally impairs granulosa and theca cell activity, altering steroid hormone production and resulting in erratic cycles
Consequently, a reduction in ATP production triggers neurodegeneration, synaptic dysfunction, and the development of cognitive impairment in AD (Butterfield and Halliwell 2019)
Even relatively small structural differences can affect how the drug binds to receptors, how long it remains active in the bloodstream, or how the immune system responds to it
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