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PMID 8980942

After 30 days, your provider will check your blood sugar and decide if you need to go up to 14 mg or not

Safety Considerations and Who Should Use Combination Therapy Combination metformin and GLP-1 therapy is generally safe for patients with adequate kidney function and no contraindications to either drug class

Edinburgh Frequently Asked Questions A next-generation investigational peptide that activates GLP-1, GIP, and glucagon receptors

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Part of it has to do with its milk thistle, which has numerous drug-drug interactions and can cause anaphylaxis in people allergic to certain plant families