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Journal of Clinical Medicine vol

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After obtaining anesthesia, patients who have a more severe sensory loss may not be able to discern between sharp (pinprick) and dull (analgesia) feelings, or they may not even be able to feel light touch at all

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Clinical studies have used schedules more intensive than those seen in recovery practice: patients with Parkinson's disease received 1,400 mg three times a week for four weeks (Hauser et al., Movement Disorders 2009, PMID 19230029), while studies on skin lightening used 1,200 mg twice a week for six weeks (Alzahrani et al., Cureus 2025, PMID 40013212)

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