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Mainstay treatments are renin-angiotensin-aldosterone system inhibitors, mineralocorticosteroid antagonists and -blockers, and, as mentioned earlier, SGLT-2 inhibitors, especially in people with comorbid diabetes

By improving nutrient signaling and reducing appetite dysregulation, GLP-1 therapies may lower stress across multiple organ systems

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The FDA approval applies to adults with cardiovascular disease and who are either obese or overweight

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