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For adults over 40, the maintenance phase is not a passive thing it requires conscious decisions about whether to stay on a maintenance dose, taper down, or come off entirely

Tirzepatide is not recommended during pregnancy because GLP-1 agonists may affect fetal development

It also may provide some protection for the cardiovascular system

This mechanism is distinct from traditional migraine preventatives and represents a novel approach to headache management through metabolic and receptor-based pathways

Some plans cover one but not the other

Combining them could increase the potential risks of these serious side effects