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After confirming that the 5% water content suppository exhibited optimal delivery, further fluorescence staining and observation of rectal tissue following administration of the 5% water content suppository were performed

An implication from those studies was that loss of CFTR might impair the function of neuroendocrine cells that express chromogranin A, and possibly alter chromogranin A expression and/or signaling

Effects of selective and non-selective cyclooxygenase inhibition against neurological deficit and brain oedema following closed head injury in mice