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126 However, we did not confirm an AT 4 -mediated natriuretic response to Ang IV in rats, although we were able to document a natriuretic response to fenoldopam, which was used as a positive control

Those with severe or long-term issues often increase their dose later

Common adverse effects include tachycardia, arrhythmias, and hypertension, and use is contraindicated in patients with idiopathic hypertrophic subaortic stenosis (IHSS), requiring careful monitoring during therapy

Jomova K, Alomar SY, Nepovimova E, Kuca K, Valko M