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Mechanisms of photoreceptor death and survival in mammalian retina

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In contrast, it has been shown that overexpression of FLNA inhibited cell motility (92) and FLNA knockdown promoted cell migration, invasion, and metastasis (93, 94), leading to the conclusion that FLNA positive or negative effect on cell motility depend on the cell type and on a balanced level of FLNA expression

This may be due to the complexation of copper to the small biologically active peptide, GHK 45

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