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Dosing concentrations designed for research titration , not calibrated for human pharmacokinetics a mismatch that has been linked in FDA adverse event reports to severe gastrointestinal illness and, in some cases, overdose from concentration errors

Each dose follows the same absorption, distribution, metabolism, and excretion (ADME) profile regardless of prior exposures

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It also has potent antioxidant and anti-inflammatory effects, reducing oxidative stress in gingival and joint tissue

While there are a lot of people who microdose because of financial restraints, microdosing is also thought to have medical benefits, such as minimizing side effects