This medication is not recommended for people with preexisting conditions, such as glaucoma, hyperthyroidism, or a history of extensive cardiovascular disease
Candidates who are ready to commit to a comprehensive planincluding dietary changes, exercise, and regular monitoringtend to experience the best outcomes
doi:10.2337/dc23-S002 37
Notably, Lys34 is replaced by arginine in its sequence, and additional structural modifications contribute to prolonging its presence in plasma, resulting in an extended half-life of approximately 7 days (165-184 hours)
Additionally, a high percentage of participants achieved a weight reduction of 5% or more (85% with 5 mg, 89% with 10 mg, and 91% with 15 mg of tirzepatide)
The package came in sealed and professionally packed