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Flavia Biamonte, Magna Grcia University of Catanzaro, Italy Updates Copyright 2022 Wang, Wang, Zhang, Zhang, Liu, Zhou, Wang and Zhang

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They developed a method to differentiate human embryonic stem (hES) cells into endocrine cells that produce key pancreatic hormones, including insulin, glucagon, somatostatin, pancreatic polypeptide, and ghrelin

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limited human data reveal no teratogenicity at therapeutic doses, yet clinicians are advised to employ the lowest effective regimen