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Collectively, this dual exhaustion effect significantly boosts OH production and improves therapeutic effect

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doi: 10.1159/000366307 68 WangC.LiL.LiuS.LiaoG.LiL.ChenY.et al

333 AG-270 is an oral selective MAT2A inhibitor that selectively inhibits the proliferation of MTAP null cells and effectively reduces the level of SAM in tumor cells in tissue and xenograft tumor models

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