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The investment is intended to upgrade, retrofit and boost capacity at the site for the firms oral GLP-1 products, which are widely used for obesity and diabetes

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Recent evidence has shown that PYR neurons expressing DA DRD1 (D1-PYR) or DRD2 (D2-PYR) exhibit differences in ion channel expression, inhibitory synaptic innervation, and subcortical projection targets ( DA activates DRD1 and DRD2 receptors in PFC, signaling by stimulating Gs or inhibiting Gi proteins respectively, as well as -arrestins, to regulate the activity of pyramidal neurons and interneurons (Zhang et al., 2017)