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Recent data indicates that both receptors may interact through -arrestin-dependent pathways, potentially contributing to their cardioprotective properties without involving G protein signaling [15]

Emmerich SD, Fryar CD, Stierman B, Ogden CL, Obesity

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doi: 10.1016/j.lfs.2020.118645 139 LeeCHJeonSJChoKSMoonESapkotaAJunHSet al

Still, these findings should be interpreted cautiously, since differences in participant characteristics and study methods can influence results