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doi:10.3389/fendo.2023.1122709 21

Patients need to discuss potential side effects with their healthcare provider to ensure safe and effective use of GLP-1 receptor agonists.

More serious risks include pancreatitis, gallbladder disease, acute kidney injury from dehydration, and hypoglycemia (when used with insulin or sulfonylureas)

2 New drugs are likely to translate to replacement spend, rather than incremental savings, at least in the short term

Although this approach is common in economic evaluations, caution should be exercised when interpreting the long-term outcomes predicted from relatively short-term clinical trial data