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Each type targets a different biological process

12.1 Key safety observations Gastrointestinal effects: The most commonly reported side effects are mild and gastrointestinal in nature

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In addition, peptide nasal sprays are known for their ease of use and convenience, because they require no needles or injections

Currently, methods to quantify intestinal absorption parameters mainly include obtaining the oral bioavailability (F) and the fraction of the drug that enters the portal vein after oral absorption (F a F g ), as well as measuring the effective permeability coefficient (P eff ) through in situ single-pass intestinal perfusion (SPIP)

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