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178 Furthermore, cyst(e)inase, a glutathione inhibitor that degrades cysteine and cystine, reduces tumor progression by elevating ROS levels and inducing tumor cell-selective ferroptosis

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Due to limited research, the roles of GPx5, GPx6, and GPx8 in tumorigenesis are still awaiting clarification

As detailed below, further time-kill assays confirm that the observed membrane damage accompanies loss of cell viability

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