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Furthermore, given its distinct mechanism of action, BRP could be explored as a complementary therapy alongside existing weight loss medications, such as GLP-1 receptor agonists

In detail, 10 L of methoxyamine (15 g/L in pyridine) was added to the dry sample that was shaken vigorously for 10 min before left to react in room temperature

25 Current ADA recommendations state that medical nutrition therapy should remain part of the treatment plan after pharmacotherapy is initiated

In a phase 2 clinical trial involving 338 adults with obesity, the highest administered dose (12 mg) resulted in an average weight reduction of 24.2% over 48 weeks

Registered dietitians, exercise specialists, primary care providers, endocrinologists, and obesity medicine practitioners can work together to support patients through the weight-loss process

The enteric coating provides additional protection, ensuring release in the small intestine where absorption occurs