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Funding Statement This review article was part of the research funded by The Japan Society for the Promotion of Science (JSPS), grant number KAKENHI JP23K28411

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Stafford, DC, and positioned for people on GLP-1 medications

These evidence-based approaches address the fundamental physiological mechanisms that influence appetite, metabolism, and weight regulation, providing a more reliable path to sustainable health improvements than unproven patches.

The Trump GLP-1 drug price deal, often referred to as TrumpRx, is a policy initiative designed to establish direct-purchase pricing tiers and negotiated options that lower patient out-of-pocket costs for select anti-obesity medications

Kennedy, however, has criticized the drugs and argued that Americans can lose weight with diet and exercise alone