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Mechanism of Action & Effectiveness: GLP-1 drugs work by slowing gastric emptying, which helps you feel full faster and for longer

employed a diet-induced NASH mouse model to compare the efficacy of cotadutide (a dual GLP-1/GCG agonist) against liraglutide (selective GLP-1 receptor agonist) and pair-fed controls

Ozempic, whose active ingredient is semaglutide, is designed to mimic the beneficial actions of natural GLP-1

However, the company views weight loss as just the starting point for a broader behavior change platform

Safe for long-term use

Thus, a deficiency of GLP-1 is now considered as part of the pathophysiology of type 2 diabetes 1