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Both semaglutide medications have risen in popularity this year for weight loss, causing a shortage of the drug in the marketplace and allowing for compounding pharmacies to make replacement medicines

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It turns out the GLP-1 mechanism is at play too: Berberine GLP-1 agonist The research community has known since 2009 -- and perhaps longer -- that berberine is a GLP-1 agonist, promoting GLP-1 amide secretion