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J Pept Sci 9:471501 Davitt K, Babcock BD, Fenelus M, Poon CK, Sarkar A, Trivigno V, Zolkind PA, Matthew SM, Grinkina N et al (2014) The anti-cancer peptide, PNC-27, induces tumor cell necrosis of a poorly differentiated non-solid tissue human leukemia cell line that depends on expression of HDM-2 in the plasma membrane of these cells

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Additionally, polyvalent melanoma vaccine has also been tried in malignant melanoma patients with minimal residual disease after resection of the tumor, which shows encouraging results with prolonged survival of several years (44)