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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, et al

In contrast, Rudman et al

Functional and phenotypic analyses confirm the induction of a pancreatic endocrine fate, including positive dithizone (DTZ) staining indicative of insulin production, as well as the upregulation of key pancreatic markers such as Nestin , PDX-1 , paired box gene 4 ( PAX4 ), neurogenin 3 ( NGN3 ), Isl-1, MAFA, insulin, and glucose transporter 2 ( GLUT2 )

For many patients, this leads to improved glycemic control and meaningful weight loss

Infusions of NAC can, however, increase brain GSH levels dramatically