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This distinction is important: insulin is traditionally measured in international units (IU), whereas peptide-based receptor agonists like retatrutide, semaglutide, and tirzepatide are dosed by weight (milligrams)

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Here is what the clinical evidence actually shows: Semaglutide (Wegovy / Ozempic) Semaglutide activates GLP-1 receptors only

Peptide therapy has been growing in popularity over the last several years due to the rejuvenation it can potentially provide and the minimal side effects associated with the treatment

Furthermore, agonism of the glucagon receptor increases energy expenditure and promotes fat loss and metabolic activity

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