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The SOUL trial met its primary endpoint by demonstrating a 14 per cent reduction in the risk of major adverse cardiovascular events (MACE) when treated with oral semaglutide versus placebo

These include: Nausea, vomiting, and diarrhea Stomach pain and constipation Heartburn and belching Your body needs time to adjust to the medication, which causes these digestive issues

However, scientists are actively working to solve this problem

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