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Given the potential adverse effects of immunosuppressive therapy, pancreas transplantation should be reserved for people with type 1 diabetes undergoing simultaneous kidney transplantation, following kidney transplantation, or for those with recurrent ketoacidosis or severe hypoglycemia despite optimized glycemic management (87)

Bondza, S., Broeke, T., ten, Nestor, M., Leusen, J

Some insurers now cover Wegovy specifically for cardiovascular risk reduction in patients with established heart disease and obesity, even when their weight-loss-only formulary excludes it

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ALP is a prognostic marker of PSC, with lower ALP levels associated with slower disease progression and fewer complications [217, 218]

Looking further ahead, findings also indicate meaningful switching intent among existing patients, with up to 500,000 open to changing treatment if price and real-world outcomes meet expectations