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Additionally, IGF-2 can also act over IGF-1R, IR and hybrid receptors but with reduced affinity [103]

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Still, its way too simplistic to just write off obesity like a math equation, take in more calories than you burn and you store all the extra as fat. To get an idea of just how complex this subject is, click on the National Library of Medicine site, affectionately known as PubMed in the medical world, and type obesity in the search bar

Journal of obesity & metabolic syndrome, 30(1), 2031.