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(accessed June 2022) 17Overweight and obesity management NICE guideline [NG246]

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These agents help manage blood glucose levels and promote weight loss in individuals with type 2 diabetes and obesity

That creates an opportunity for practicesbut the durable opportunity lies in clinical credibility, not in presenting every patient as a surgical lead

Because abnormal epigenetic marks disrupt the expression of specific tumor suppressor genes in cancer cells, compounds that re-induce their transcription, like those inhibiting HDACs, can potentially promote differentiation and apoptosis in transformed (precancerous) cells (37)

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