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JAMA Network Open, 5 (1), e2144279

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The Renin-Angiotensin-Aldosterone System (RAAS) It is well known that the RAAS is one of the most important regulators of arterial blood pressure, with a key role in cardiovascular and renal diseases, mainly mediated by inflammatory processes ( The cascade of the systemic RAAS starts with the liver angiotensinogen (AGT), which is converted to Angiotensin I (ANG I) by renin, a hormone secreted by the juxtaglomerular cells