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Mice bearing IMR5 xenografts with a mean diameter of 5 mm were treated with 3 mg/kg DPI (P.O., 5 days/week), 30 mg/kg MitoQ (P.O., 3 days/week), or their combination (1.5 mg/kg DPI (P.O., 5 days/week) and 20 mg/kg MitoQ (P.O., 3 days/week))

Fundamentally, this substance is synthesized from lysine (an essential amino acid)

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Leucine is not only a precursor for muscle protein synthesis, but is also a regulator of intracellular pathways that are involved in the process of protein synthesis

This action reduces antigen translocation, and effectively blocks the source of systemic immune activation, thus providing a multifaceted strategy to mitigate immune-related pathologies