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These studies were carried out with exenatide and liraglutide in a rat model of diabetes, and they increased concerns with respect to the possible adverse effects of GLP-1 mimetic therapy on exocrine pancreas

This is medically known as dysgeusia

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Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H et al (2014) Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity

(2011) Growth temperature-dependent expression of structural variants of Listeria monocytogenes lipoteichoic acid Immunobiology, 216, 2431 6

GLP-1s lack the stigma of addiction-specific treatments, and physicians are already familiar with prescribing them