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Off-the-shelf proximity biotinylation for interaction proteomics

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The release of P i is coupled with rotamer exchanges in the arginine finger loop

doi: 10.1016/j.tem.2019.05.008 29 FujiiT.SatoK.OzawaM.KasonoK.ImamuraH.KanajiY.et al

Consistently, GSTP-S184D also showed higher efficiency than GSTP (WT) in preventing LPS-induced HMGB1 export from the nucleus to cytoplasm in RAW264.7 cells, while GSTP-S184A almost had no effect on that (Figure 5B)

The study suggests that GLP-1 therapy in this group led to increased costs without clear health benefits over the observed period