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STF-31 is a small-molecule inhibitor of NAMPT that selectively kills renal cell carcinoma cells upon the loss of the von Hippel-Lindau (VHL) tumor suppressor gene

For the HEDS assays, either GSH was varied between 100 M and 1.5 mM for ScGrx (or 250 M and 3.0 mM for PfGrx) at fixed concentrations of HEDS (0.18, 0.37, 0.55 and 0.74 mM) or HEDS was varied between 90 and 920 M at fixed concentrations of GSH (0.3, 0.5, 1 and 1.5 mM for ScGrx7 or 0.25, 0.5, 1 and 2 mM for PfGrx)

doi: 10.1021/acsinfecdis.1c00428 244 WangchukP.ConstantinoiuC.EichenbergerR

This origin explains why the peptide shows such powerful tissue-protective and regenerative properties throughout the body

The study conducted a series of experiments to determine the optimal concentration of DTNB for the assay

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