The Takeaway SURPASS-CVOT could be a watershed moment for diabetes management, providing the first head-to-head evidence that dual incretin receptor activation helps protect the heart while delivering clinically meaningful advantages in mortality and kidney preservation
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Mean differences in post-cessation weight gain between the treatment and control groups included 2.9 kg (95% CI, 3.53 to 2.27) in the Swiss study, 1.56 kg (95% CI, 3.58 to 0.45) in the study, and 2.59 (95% CI, 3.7 to 1.48) overall
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Retatrutide Dosing Guide Standard titration schedule (2mg to 12mg), dose escalation timing, and what Phase 2 trial data shows about each dose level
Sci Rep 10:14738 Muccee F, Naeem MA, Razak S, Afsar T, Hussain N, Mabood HF, Shafique H (2024) Exploring the association of ESR1 and ESR2 SNPs with polycystic ovary syndrome in females
