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En el presente estudio, los niveles plasmticos de T4 se redujeron significativamente con altas dosis de suplemento de L-carnitina (250 mg/L)

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Further investigations showed that GLP-1R-mediated cAMP responses were reduced in islets extracted from these mice, suggesting that a high cholesterol diet specifically impacts on beta cell GLP-1R activity

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This distinction is crucial when comparing these findings with clinical trials involving patients with established symptomatic disease