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Lysyl oxidases: from enzyme activity to extracellular matrix cross-links

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We calibrate and validate the model using experimental measurements, at different postnatal days up to PN28, from control mice and from the rd1 mouse model for the disease retinitis pigmentosa (RP)

Elevated SAH, Glutathione and Undermethylation Toxic overload and depression may be connected when environmental exposures, gut-derived toxins, oxidative stress, glutathione depletion and impaired clearance reduce neurological resilience