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The baseline remains 12 weeks across the activation, remodeling, and maintenance phases

Genetic Predisposition in Triglyceride Metabolism and Treatment Response Variants in genes controlling lipid metabolismincluding GIPR, GLP1R, and genes regulating hepatic triglyceride synthesisinfluence baseline triglyceride levels and individual response to GLP-1 therapy

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Consequently, their safety profile and efficacy in Crohn's patients, particularly those with active inflammation or stricturing disease, has not been comprehensively established

For a performance-minded reader, that matters