And probably also adjusts intake to the digestive capacity of the gut
The atherogenicity of Lp(a) is substantially greater than that of LDL on a per-particle basis, and elevated Lp(a) has been established as an independent risk factor for ASCVD, particularly in individuals with high LDL-C
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In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (Cuadrado et al., 2019
This dual mechanism creates a two-pronged approach
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