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GHK-Cu works through different mechanisms Wnt pathway activation, anti-inflammatory signaling, reduced androgen receptor sensitivity but it doesn't directly block DHT the way finasteride does, and it doesn't open potassium channels like minoxidil

Vigorous agitation can denature the peptide

The decision to pursue a 1-cm versus 2-cm margin should be based on patient and lesion factors, including functional and cosmetic limitations

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Premature patch removal or extended wear time : Removing a patch before the prescribed duration or leaving it on beyond the recommended time can compromise treatment effect